Super rat hotspots N, S, E and W surround central data void

Super rat hotspots N, S, E and W surround central data void

New hotspots of rats that are resistant to anticoagulant rodenticides have been identified by monitoring carried out at The University of Reading. The study was commissioned by the Campaign for Responsible Rodenticide Use (CRRU) under its stewardship remit for the HSE-led Government Oversight Group (GOG).

In East Anglia and West Yorkshire, it identifies for the first time the L120Q gene, responsible for the most severe form of resistance. This gene renders first generation anticoagulant rodenticides and two of the second generation groups ineffective. It is widespread across the whole of central southern England and also found increasingly outside that area.

Another serious concern is that three different types of resistant rats are now found in West Yorkshire and on the Anglo-Welsh border. Also a worry is the almost complete lack of data from central England.

According to co-author of the The University of Reading report Dr Colin Prescott, it is not known whether resistance is present in the central region or not. “The few samples we do have show that rats are mostly susceptible to anticoagulants, but we need many more to be confident of this,” he says.

Although the study covers mice as well as rats, only nine new mouse samples were sent to Reading in 2018 and these continue to show very high incidence of resistance. In all, 89% of mice tested were highly resistant to anticoagulants. CRRU chairman Dr Alan Buckle says more samples from both rats and mice are desperately needed.

“We can only manage the spread of resistance when we know where it is,” he says. “With so few mouse samples and the void of rat data in the centre of the country, we are a long way from that.

“Presently we have the worst of both worlds. Farmers, pest control technicians and gamekeepers are using products that are ineffective in places where rodents are resistant; and they are using unnecessary, resistance-breaking products where there is no resistance. Only more samples can solve this.”

Professional rodenticide users interested in sending tissue samples for analysis should first contact the University of Reading at

Dr Buckle adds that all rodenticide users are obliged to follow the CRRU Code of Best Practice, which includes monitoring the results of control treatments. “If this suggests that rodents are surviving well-implemented control programmes, this may indicate the presence of resistance,” he suggests. “Those struggling to control resistant rodents can call on the services of a reputable professional pest control company.”

The report was requested by GOG because new stewardship authorisations under the Biocidal Products Regulations, the promotion of best practice through the stewardship regime, and the emphasis in stewardship on the use of alternatives to anticoagulants, will all play a part in managing resistant rodent infestations, preventing their spread.

The report, available HERE, is updated and published annually as part of the UK Rodenticide Stewardship Regime’s monitoring programme.